Businessman Vivek Ramaswamy has won the Republican primary for Ohio governor, according to multiple news projections, setting up a November general election matchup against Democrat Amy Acton.

Ramaswamy, who received backing from former President Donald Trump, defeated his primary opponents to secure the GOP nomination for the open gubernatorial seat. The race is to replace term-limited Governor Mike DeWine, a Republican who has endorsed Ramaswamy.

Acton, a former Ohio Department of Public Health director, won the Democratic primary and will face Ramaswamy in what is expected to be a competitive and potentially expensive general election campaign. Ohio has proven challenging territory for Democrats in recent election cycles.

The gubernatorial contest is part of a broader set of primary elections that took place Tuesday in Ohio and other states. Several other Ohio House races also saw primary winners advance to November matchups, including Rep. Marcy Kaptur facing a rematch against former state Rep. Derek Merrin, and Rep. Greg Landsman set to face Republican Eric Conroy.

Ramaswamy, a biotech entrepreneur who previously ran for the Republican presidential nomination, will now focus his campaign on the general election in a state that has generally favored Republican candidates in statewide races in recent years.