Barcelona faced Newcastle United at home in the second leg of their UEFA Champions League round of 16 matchup on Tuesday.

The Spanish club had taken the lead in the match when they were dealt a setback as a key defender was substituted due to a possible injury. The nature and severity of the injury were not immediately clear.

The match represented the decisive second leg of the two-legged tie, with both teams vying for a place in the Champions League quarterfinals. Barcelona entered as hosts looking to advance past the English Premier League side.

The injury concern added complications for Barcelona's European campaign, as defensive stability has been crucial to their success this season. The substitution came at a particularly inconvenient time given the importance of the knockout stage match.